Description: Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of the intracellular adhesion molecule-1 (ICAM-1) in fibroblasts. (www.uniprot.org) Produced in E.coli as a homodimeric, non-glycosylated polypeptide chain containing a total of 264 amino acids.IL-17 regulates the activities of NF-kappaB and mitogen-activated protein kinases.