Interleukin-28B, mouse recombinant (rmIL-28B)

Kategorie: Cytokines

Formulation: lyophilized

Storage: -20°C

Weight: 19600 D

Purity: >97%

Description: IL-28B mouse recombinant produced in E. coli is a single, non-glycosylated polypeptide chain containing 174 amino acids and having a molecular mass of 19.6 kDa. IL-28B is a cytokine remotely related to type I interferons and the IL-10 family. Interleukin-28B, interleukin 28A (IL28A), and interleukin 29 (IL29) are 3 closely related cytokine genes which form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by these 3 genes can be induced by viral infection. All 3 cytokines interact with a heterodimeric class II cytokine receptor which consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). The ED50 as determined by an anti-viral assay using human HepG2 cells infected with encephalomyocarditis is less than 30 ng/ml, corresponding to a specific activity of > 3.3 × 104 IU/mg.

• Artikelnummer: BOL97641.20
• Hersteller: Biomol
• Hersteller Artikelnummer: 97641.20
• Green Labware: Nein
• Verpackungseinheit: 20 µg
• Mengeneinheit: STK
• Reaktivität: Mouse (Murine)
• Human Gene ID: 338374
• Wirt: Escherichia Coli