Interleukin-4, HEK, human recombinant (rHuIL-4-HEK)

Kategorie: Cytokines

Formulation: lyophilized

Storage: -20°C

Purity: >95%

Description: Human recombinant IL-4 produced in HEK cells is a glycosylated monomer, having a molecular weight range of 14-19kDa due to glycosylation. IL-4 is a pleiotropic cytokine produced by activated T cells. IL-4 is a ligand for interleukin-4 receptor. The interleukin-4 receptor also binds to IL-13, which may contribute to many overlapping functions of this cytokine and IL-13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL-13. IL-4, IL-13 and IL-5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

• Artikelnummer: BOL97518.1
• Hersteller: Biomol
• Hersteller Artikelnummer: 97518.1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Reaktivität: Human
• Human Gene ID: 3565
• Wirt: Human