Interleukin-4, Rhesus Macaque recombinant (rrmIL-4)

Kategorie: Cytokines

Formulation: lyophilized

Storage: -20°C

Weight: 14900 D

Purity: >97%

Description: Rhesus Macaque recombinant IL-4 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 129 amino acids and having a molecular mass of 14.9kDa. IL-4 is a pleiotropic cytokine produced by activated T-cells. IL-4 is a ligand for interleukin-4 receptor. The interleukin-4 receptor also binds to IL-13, which may contribute to many overlapping functions of this cytokine and IL-13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL-13. IL-4, IL-13 and IL-5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

• Artikelnummer: BOL97592.1
• Hersteller: Biomol
• Hersteller Artikelnummer: 97592.1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Reaktivität: Rhesus Monkey (Primate)
• Wirt: Escherichia Coli