Macrophage-Derived Chemokine (CCL22), mouse recombinant (rmMDC)

Kategorie: Cytokines

Formulation: purified

Storage: -20°C

Weight: 7800 D

Purity: >97%

Description: Chemotactic for activated T-lymphocytes. May play an important role in the collaboration of dendritic cells and B-lymphocytes with T-cells in immune responses. (www.uniprot.org) CCL22 Mouse Recombinant produced in E.coli is a non-glycosylated, Polypeptide chain containing 68 amino acids and having a molecular mass of 7.8kDa. The Mouse CCL22 is purified by proprietary chromatographic techniques. MDC (CCL22) is a small cytokine that belongs to the CC chemokine family. CCL22 is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. MDC shows chemotactic activity for natural killer cells, chronically activated T lymphocytes, monocytes and dendritic cells. On the other hand, MDC shows a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes. MDC may also have a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology. MDC interacts with cell surface chemokine receptors CCR4.

• Artikelnummer: BOL97316.1
• Hersteller: Biomol
• Hersteller Artikelnummer: 97316.1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Reaktivität: Mouse (Murine)
• Wirt: Escherichia Coli