Description: Strongly chemotactic for naive (L-selectinhi) CD4 T-cells and for CD8 T-cells and weakly attractive for resting B-cells and memory (L-selectinlo) CD4 T-cells. May play a role in promoting encounters between recirculating T-cells and dendritic cells and in the migration of activated B-cells into the T-zone of secondary lymphoid tissues. Specifically binds to chemokine receptor CCR7. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 83 amino acids. CCL19 elicits its effects on its target cells by binding to the chemokine receptor chemokine receptor CCR7.