Kategorie: Cytokines
Formulation: lyophilized
Storage: -20°C
Weight: 8.6 kD
Purity: >97%
Description: Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. (www.uniprot.org) Produced in E.coli as a non-glycosylated, polypeptide chain containing 76 amino acids. CCL2 recruits immune cells, such as monocytes, to sites of tissue injury and infection.