RELM-beta, mouse recombinant (rmRELM-b)

Kategorie: Cytokines

Formulation: purified

Storage: -20°C

Weight: 8800 D

Description: Recombinant mouse RETNLB produced in E.coli is a monomeric, non-glycosylated, polypeptide chain containing 83 amino acids and having a molecular mass of 8.8 kDa. RELM-beta (Resistin-Like Molecule-beta) is a member of a recently identified family of secreted proteins containing a conserved cystein-rich C-terminus. The RELM family consists of resistin (also called FIZZ3), RELM-alfa (FIZZ1), RELM-beta (FIZZ2) and RELM-gamma. Only resisistin and RELM-beta were found in humans whereas all four RELM family members were identified in rodents. RELM-beta appears to be produced as a homodimer exclusively by intestinal goblet cells and can be found in high quantities in stool. Remarkably, stool of germ-free mice displaying sterile intestinal tract does not contain RELM-beta until bacterial colonization takes place after pathogen-free mice entered natural environment. Some, but not all, colon carcinoma cell lines secrete RELM-beta into the cell culture supernatant.

• Artikelnummer: BOL97382.25
• Hersteller: Biomol
• Hersteller Artikelnummer: 97382.25
• Green Labware: Nein
• Verpackungseinheit: 25 µg
• Mengeneinheit: STK
• Reaktivität: Mouse (Murine)
• Wirt: Escherichia Coli