Tumor Necrosis Factor Receptor Fusion Protein, human recombinant (rHuTNFR-CHO)

Kategorie: Cytokines

Formulation: lyophilized

Storage: -20°C

Purity: >98%

Description: Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity. (www.uniprot.org) Produced in CHO as a dimeric, glycosylated, polypeptide chain consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1.

• Artikelnummer: BOL94971.1
• Hersteller: Biomol
• Hersteller Artikelnummer: 94971.1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Reaktivität: Human
• Wirt: Hamster