FCGR2A (CD32A) Knockout Jurkat Cell Line

FCGR2A (CD32A) Knockout Jurkat Cell Line
Artikelnummer
BPS78549
Verpackungseinheit
2 vials
Hersteller
BPS Bioscience

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Applications: Use as a control for characterizing FCGR2A in T cells

Background: FCGR2A (also known as CD32A) encodes a low affinity Fc receptor for immunoglobulin G. FcγRIIa is a cell surface receptor expressed on a variety of immune cells such as macrophages and neutrophils. It is involved in phagocytosis and in the clearing of spent immune complexes from the circulation. A polymorphism in FcγRIIa is associated with increased risks of nephritis and lupus.

Description: The FCGR2A Knockout Jurkat cell line was generated by CRISPR/Cas9 genome editing to remove FCGR2A (CD32A), the gene encoding protein FcγRIIa (Fragment crystallizable gamma receptor II a, also known as FcGRIIa, Fc-gamma-RIIa, and CD32A).

Host Cell Line: Jurkat (clone E6-1), human T lymphoblast, suspension

Mycoplasma Testing: The cell line has been screened to confirm the absence of Mycoplasma species.

Storage Stability: Cells are shipped in dry ice and should immediately be thawed or stored in liquid nitrogen upon receipt. Do not use a -80°C freezer for long term storage.

Supplied As: Each vial contains 2 x 106 cells in 1 ml of cell freezing medium (BPS Bioscience #79796)

Warnings: Avoid freeze/thaw cycles.

Biosafety Level: BSL-1
Mehr Informationen
Artikelnummer BPS78549
Hersteller BPS Bioscience
Hersteller Artikelnummer 78549
Green Labware Nein
Verpackungseinheit 2 vials
Mengeneinheit PAK
Wirt Human
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