Formulation: A solid
Formal Name: (T-4)-bis[1-(hydroxy-κO)-2(1H)-pyridinethionato-κS2]-zinc
Purity: ≥95%
Formula Markup: C10H8N2O2S2Zn
Formula Weight: 317,7
Shelf life (days): 1460
CAS Number: 13463-41-7
Notes: Zinc pyrithione is a coordination complex of zinc and pyrithione that has antimicrobial, anticancer, and fungicidal activities.{47777,47778,47779,66488} It is active against the bacteria E. coli, S. aureus, K. pneumoniae, A. baumannii, P. aeruginosa, E. faecium, E. faecalis, and E. cloacae (MICs = 1-4 µg/ml) and the fungus P. ovale when used at concentrations ranging from 0.01 to 10 µg/ml.{47777,47778} Zinc pyrithione reduces tumor growth in an SCC-4 mouse xenograft model when administered at a dose of 1 mg/kg per week for six weeks.{47779} Topical application of zinc pyrithione (0.5-5% w/w) completely prevents Aspergillus growth in soy meal-derived adhesives.{66488} Formulations containing zinc pyrithione have been used in the treatment of dandruff and in the prevention of fungal growth in industrial applications.
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