The Zymo-Seq RRBS Library Kit is an all-inclusive library prep kit for low-input library preparation fo Reduced Representation of Bisulfite Sequencing (RRBS) to profile genome-wide DNA methylation.
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Description: Zymo-Seq RRBS Library Kit is an all-in-one library preparation kit to generate DNA methylation libraries with a simplified workflow for the classic method Reduced Representation Bisulfite Sequencing (RRBS). This all-in-one library preparation kit allows for DNA methylation profiling at single-nucleotide resolution in CpG-rich regions of the genome. Zymo-Seq RRBS Library Kit generates libraries that cover a significant percent (≥70% if using human genomic DNA) of all CpG islands, promotors, and gene bodies while largely reduces the sequencing cost, making it ideal for pilot studies and comparison experiments.
Simple workflow: Prepare Reduced Representation Bisulfite Sequencing (RRBS) libraries in as little as 2 hours of hands-on time.
Low input: The only RRBS kit that produces NGS libraries from ≥ 10 ng of genomic DNA.
Accurate and reproducible: Unbiased methylation calling and reproducible CpG coverage.