1-Cbz-azetidine-3-carboxylic acid, CAS 97628-92-7

Product Description: 1-Cbz-azetidine-3-carboxylic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 1-Cbz-azetidine-3-carboxylic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]
Applications: Cancer-programmed cell death

Formula: C12H13NO4

References: [1]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985./[2]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337.

CAS Number: 97628-92-7

Molecular Weight: 235.24

Compound Purity: 99.50

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Linker;PROTAC Linkers

• SKU: MEXHY-W004868-10G
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W004868-10G
• Package Unit: 10 g
• Quantity Unit: STK