Clone Name: AT4B9
Light Chain: Kappa
Application Note: WB: Recommended starting dilution is 1:1000.. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 28
Specificity/Sensitivity: Based on internal testing result, this antibody does not cross react with human YWHAZ, human YWHAB, human YWHAE, human YWHAH, human SFN, and human YWHAQ.
Form: Liquid
Buffer (with preservative): PBS, 10% Glycerol, 0.02% Sodium azide.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways. [provided by RefSeq, Jul 2008]
Uniprot ID: P61981
Antigen Species: Human
Immunogen: The clone AT4B9 is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human 14-3-5 gamma protein.
Purification: Protein A Purified
Conjugation: Unconjugated
Full Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
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