Abatacept Biosimilar - Research Grade

Abatacept Biosimilar - Research Grade, Host: CHO Cells

Target: CTLA-4 Fc Fusion Protein.

Specificity: Fusion protein of a Fc fragment (human IgG1 isotype) and the extracellular domain of CTLA-4.

Purification method: This fusion protein was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Background: Recombinant protein composed of the extracellular domain of CTLA-4 fused with the Fc region of human immunoglobulin gamma 1 (hIgG1). Abatacept binds to CD80 (B7-1) with more avidity than to CD86 (B7-2).

Concentration: 5mg/ml.

Formulation: Sterile, preservative-free, solution in PBS. BSA and Azide free.

Purity: ≥95% monomer by analytical SEC, >95% by SDS Page.

Endotoxin: <1EU/mg Determined by LAL gel clotting assay.

Use: Products are for research use only. Not for use in diagnostic or therapeutic procedures.

• SKU: ICH5185-10MG
• Manufacturer: Ichorbio
• Manufacturer SKU: ICH5185-10MG
• Package Unit: 10mg
• Quantity Unit: STK
• Reactivity: Human
• Application: Functional Assay
• Host: Cell Line