Abbreviation: ABCA7
Target Synonym: ABCA7;ABCA-SSN;ABCX;AD9
Conjugation: Unconjugated
UNIProt ID: Q8IZY2
Background: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This full transporter has been detected predominantly in myelo-lymphatic tissues with the highest expression in peripheral leukocytes, thymus, spleen, and bone marrow. The function of this protein is not yet known; however, the expression pattern suggests a role in lipid homeostasis in cells of the immune system.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human ABCA7
Dilution: WB 1:500-1:2000,IF 1:50-1:200
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