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Application Note: WB: 1:200-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 105
Form: Liquid
Buffer (with preservative): PBS pH 7.4, 40% Glycerol, 0.05% Sodium azide.
Concentration: 0.7 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) and ADAMTS-like protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene lacks the protease domain, and is therefore of a member of the the ADAMTS-like protein subfamily. It is a secreted glycoprotein that binds the cell surface and extracellular matrix; it also interacts with latent transforming growth factor beta binding protein 1. Mutations in this gene have been associated with geleophysic dysplasia. [provided by RefSeq, Feb 2009]
Uniprot ID: Q86TH1
Antigen Species: Human
Immunogen: Recombinant fusion protein corresponding to residues near the C terminal of human ADAMTS-like 2
Purification: Purified by antigen-affinity chromatography
Conjugation: Unconjugated
Full Name: ADAMTS like 2