Abbreviation: AK2
Target Synonym: AK2;ADK2
Conjugation: Unconjugated
UNIProt ID: P54819
Background: Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates; this gene encodes isozyme 2. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Mutations in this gene are the cause of reticular dysgenesis. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1 and 2.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human AK2
Dilution: WB 1:500-1:2000
English
Deutsch
