Conjugation: HRP: Horseradish Peroxidase
Description of Target: This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a cytosolic isoform, which has a high affinity for aldehydes.
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ALDH1A1
Molecular Weight: 55kDa
Peptide Sequence: Synthetic peptide located within the following region:
SVERAKKYILGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGProduct Format: Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Protein Name: Retinal dehydrogenase 1
Protein Size: 501
Purification: Affinity Purified
English
Deutsch
