Clone Name: 2A7
Application Note: WB: 1:1000. ICC/IF: 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 14
Form: Liquid
Buffer (with preservative): PBS, 50% glycerol, 5mM sodium azide.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016]
Uniprot ID: P37840
Antigen Species: Human
Immunogen: Full length human recombinant protein expressed in and purified from E. coli
Purification: Purified IgG1
Conjugation: Unconjugated
Full Name: synuclein alpha
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