Product Description: Aminohexylgeldanamycin (AHGDM), a Geldanamycin derivative, is a potent HSP90 inhibitor. Aminohexylgeldanamycin shows antiangiogenic and antitumor activities[1].
Applications: Cancer-programmed cell death
Formula: C34H52N4O8
References: [1]Greish K, et al. Anticancer and antiangiogenic activity of HPMA copolymer-aminohexylgeldanamycin-RGDfK conjugates for prostate cancer therapy. J Control Release. 2011;151(3):263-270./[2]Larson N, et al. HPMA copolymer-aminohexylgeldanamycin conjugates targeting cell surface expressed GRP78 in prostate cancer. Pharm Res. 2010;27(12):2683-2693.
CAS Number: 485395-71-9
Molecular Weight: 644.80
Compound Purity: 99.82
Research Area: Cancer
Solubility: DMSO : 110 mg/mL (ultrasonic)
Target: ADC Cytotoxin;HSP