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Applications: This antibody crosslinked with FcGR2B is useful for activation of CD27 costimulatory pathway in T cells.
Description: Anti-CD27 agonist antibody binds to CD27 on T cells and promotes T cell response. It represents new opportunities for cancer immunotherapy.
Format: Aqueous buffer solution
Formulation: 8 mM Na Phosphate pH 7.4, 110 mM NaCl, 2.2 mM KCl and 20% glycerol.
Purification: Protein A affinity chromatography from HEK293 supernatants.
Storage Stability: Stable for at least 12 months at -80°C.
Uniprot: P26842
Warnings: Protect from light. Avoid freeze/thaw cycles. Store diluted antibody with carrier protein (BSA 0.1 - 0.5%) at 4°C, stable for 2 weeks.
Biosafety Level: Not applicable (BSL-1)
References: Vitale, L., et al., Clin Cancer Res. 2012; 18(14): 3812-3821.
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