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Application: Useful for studying the expression of FOLR1 on the cell surface by flow cytometry.
Background: Folate receptor alpha (FOLR1) is a glycosylphosphatidylinositol (GPI)-anchored membrane protein that transports folate (vitamin B9) into cells. FOLR1 is overexpressed in multiple cancers such as cervical cancer, ovarian cancer, breast cancer, and brain carcinomas, and FOLR1 overexpression is associated with poor patient prognosis and increased cancer progression. The overexpression of FOLR1 in a variety of cancerous tissues makes it a valuable target for drug development. There are currently multiple drugs in clinical trials that target FOLR1.
Cross Reactivity: This antibody recognizes human FOLR1. It has not been tested in other species.
Description: This anti-FOLR1 (Folate receptor alpha) antibody is a purified monospecific recombinant antibody, which is labeled with fluorescein isothiocyanate (FITC). This antibody has been tested by flow cytometry for specific binding to human FOLR1 on the surface of FOLR1 CHO Cell Line (BPS Bioscience #78360).
Format: Aqueous buffer solution.
Formulation: 8 mM Phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, 0.09% Sodium Azide, 0.2% BSA, and up to 20% glycerol. May contain a protein stabilizer.
Purification: Protein A affinity chromatography from HEK293 supernatant.
Purity: ≥90%
Storage Stability: At least 6 months at +4°C. Protect from prolonged exposure to light. DO NOT FREEZE. The antibody solution should be stored undiluted between +2°C and +8°C.
Uniprot: P15328
Warnings: Do not freeze. Protect from light.
Biosafety Level: Not applicable (BSL-1)
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