Anti-PspA (2B11)

Anti-PspA [2B11], Recombinant, IgG1 lambda, Mouse

CloneID: 2B11

Antigen Long Description: The original antibody was selected from a synthetic human scFv library through biopanning against recombinant PspA.

Buffer Composition: PBS only.

Uniprot Accession No.: A0A1M4NIX2

Specificity Statement: This antibody is specific for the Streptococcus pneumoniae PspA. The epitope on PspA was defined to residues 231-242 by mutational analysis and supported by molecular docking analysis.

Application Notes (Clone): The dissociation constant (K_d) of the original human scFv version of this antibody was 5.3 ± 2.3 nM as measured in a biolayer interferometry assay. This antibody detected PspA in immunoblots; it exhibited a dose-dependent recognition of recombinant PspA with no cross-reactivity towards other tested pneumococcal antigens and also detected endogenous PspA from pneumococcal lysates (Jang et al., 2017; PMID: 27845043).

• SKU: ABAAb04716-1.1-BT
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab04716-1.1-BT
• Package Unit: 1 mg
• Quantity Unit: STK
• Reactivity: Various species
• Clonality: Recombinant
• Application: ELISA, Immunoblotting, BLI Binding Assay
• Isotype: IgG1 lambda
• Host: Mouse