APL-1081, CAS 2921735-80-8

Product Description: APL-1081 (Mal-Exo-EVC-MMAE) is part of an antibody-conjugated active molecule (ADC). APL-1081 is conjugated with an ADC linker (peptide Mal-Exo-EEVC) and a potent tubulin polymerization inhibitor, MMAE (HY-15162)[1].

Applications: Cancer-programmed cell death

Formula: C75H115N13O19

References: [1]Watanabe T, et al. Exo-Cleavable Linkers: Enhanced Stability and Therapeutic Efficacy in Antibody–Drug Conjugates[J]. Journal of Medicinal Chemistry, 2024.

CAS Number: 2921735-80-8

Molecular Weight: 1502.79

Compound Purity: 99.79

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Drug-Linker Conjugates for ADC;Microtubule/Tubulin

• SKU: MEXHY-169322-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-169322-10
• Package Unit: 10 mg
• Quantity Unit: STK