APN-PEG36-tetrazine

Product Description: APN-PEG36-tetrazine is an analogue of APN-PEG4-tetrazine. APN-PEG4-tetrazine is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. APN-PEG36-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

Applications: Cancer-programmed cell death

Formula: C94H161N7O38

References: [1]Beck A, et, al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Molecular Weight: 1997.30

Compound Purity: 96.05

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)

Target: ADC Linker

• SKU: MEXHY-139859-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-139859-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK