ARC Polyclonal Antibody

Formulation: 500 µl of Peptide affinity-purified polyclonal antibody

Immunogen: Synthetic peptide from the C-terminal region of human ARC

Shelf life (days): 1095

Notes: Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD domain-containing cell death regulators included RAIDD, Apaf-1, caspase-9, and caspase-2. A novel CARD domain containing protein was recently identified and designated ARC for apoptosis repressor with CARD.{7140} ARC interacts with caspase-2 and -8 and inhibits enzymatic activity of caspase-8. ARC suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR-1 and DR3. The mRNA for ARC is expressed primarily in skeletal muscle and cardiac tissues.{7140}

• SKU: CAY160737-500
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 160737-500
• Green Labware: No
• Package Unit: 1 ea (500 µl)
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Polyclonal
• Application: Immunoprecipitation, Western Blotting
• Host: Rabbit