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Encompassing Amino Acids: 981 - 1108
Applications: Useful for the study of bromodomain binding assays, screening inhibitors, and selectivity profiling.
Description: Human Bromodomain ATAD2A, also known as ANCCA and ATPase Family AAA Domain-containing Protein 2, GenBank Accession No. NM_014109, a.a. 981 - 1108 corresponding to single bromodomain with N-terminal GST-tag, MW = 42 kDa, expressed in an E. coli expression system.
Format: Aqueous buffer solution
Formulation: 45 mM Tris-HCl, pH 8.0, 124 mM NaCl, 2.4 mM KCl, and 10% glycerol.
Genbank: NM_014109
Storage Stability: At least 6 months at -80°C.
Tags: N-terminal GST-tag
Uniprot: Q6PL18
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Caron C, et al., Oncogene. 2010 Sep 16; 29(37):5171-81.
2. Kalashnikova EV, et al.,Cancer Res. 2010 Nov 15; 70(22):9402-12.