Azvudine, CAS 1011529-10-4

Formulation: A solid

Formal Name: 4-amino-1-(4-C-azido-2-deoxy-2-fluoro-β-D-arabinofuranosyl)-2(1H)-pyrimidinone

Purity: ≥95%

Formula Markup: C9H11FN6O4

Formula Weight: 286,2

Shelf life (days): 1460

CAS Number: 1011529-10-4

Notes: Azvudine is a nucleoside reverse transcriptase inhibitor (NRTI).{68537} It reduces viral infectivity in HIV-1-infected HEK293T cells (EC50 = 0.063 nM) and reduces viral replication in 2209-23 cells stably transfected with hepatitis C virus (HCV) genotype 1b (EC50 = 24 nM).{68537,68538} In vivo, azvudine (0.7 mg/kg) reduces viral load and the number of lung ground-glass opacities observed via chest X-ray in a rhesus macaque model of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.{68539}

• SKU: CAY37669-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 37669-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK