Formulation: A solid
Formal Name: L-isoleucyl-L-arginyl-L-isoleucyl-L-isoleucyl-L-leucyl-L-arginyl-L-alanyl-L-glutaminylglycyl-L-alanyl-L-leucyl-L-lysyl-L-isoleucine, trifluoroacetate salt
Purity: ≥85%
Formula Markup: C67H125N21O15 • XCF3COOH
Formula Weight: 1464,8
Shelf life (days): 1460
Notes: BING is an antimicrobial peptide that has been found in Japanese medaka fish (O. laptipes) and is derived from vacuolar protein sorting-associated protein 13D-like (Vps13D).{65840} It is active against various Gram-negative and Gram-positive bacteria, including methicillin-resistant S. aureus (MRSA; MICs = 4-64 µg/ml). BING is synergistic with the antibiotics ampicillin (Item Nos. 14417 / 35740), amoxicillin (Item No. 19188), and novobiocin (Item No. 18457) against P. aeruginosa and suppresses the development of resistance to kanamycin and ampicillin in E. coli. In vivo, BING increases the survival rate of O. laptipes infected with E. tarda.
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