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Encompassing Amino Acids: 561-668
Applications: Useful for the study of bromodomain binding assays, screening inhibitors, and selectivity profiling.
Description: Human Bromodomain containing 1, also known as BRD1 and BRL, GenBank Accession No. NM_014577, a.a. 561 - 668 corresponding to single bromodomain with N-terminal GST-tag, MW = 40 kDa, expressed in an E. coli expression system.
Format: Aqueous buffer solution
Formulation: 50 mM Tris-HCl, pH 8.0, 138 mM NaCl, 2.7 mM KCl, 1 mM EDTA, 10% glycerol, and 1 mM DTT
Genbank: NM_014577
Storage Stability: At least 6 months at -80°C.
Tags: N-terminal GST-tag
Uniprot: O95696
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Mishima, Y., et al., Blood. 2011 Sep 1; 118(9): 2443-2453.
2. Severinsen, JE., et al., Mol. Psychiatry. 2006 Dec; 11(12): 1126-1138.