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Encompassing Amino Acids: 65-459
Applications: Useful for the study of bromodomain binding assays, screening inhibitors, and selectivity profiling.
Description: Human Bromodomain containing 2, also known as BRD2, RING3 or RNF3, GenBank Accession No. NM_005104, a.a. 65 - 459 corresponding to bromodomains 1 and 2 with N-terminal His-tag, MW = 45 kDa, expressed in an E. coli expression system.
Format: Aqueous buffer solution
Formulation: 45 mM Tris-HCl, pH 8.0, 124 mM NaCl, 2.4 mM KCl, 10% glycerol.
Genbank: NM_005104
Storage Stability: At least 6 months at -80°C.
Tags: N-terminal His-tag
Uniprot: P25440
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Umehara, T., et al., FEBS Lett. 2010 Sep 24; 584(18): 3901-3908
2. Shang, E., et al., J Cell Biochem. 2011 Oct; 112(10): 2784-2793