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Encompassing Amino Acids: 956-1390(end) with del 963-109 (exon 14)
Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Description: Human MET, also known as Proto-Oncogene c-Met, HGF Receptor (HGFR), AUTS9 and SF Receptor, GenBank Accession No. NM_000245, a.a. 956-1390(end) with deletion a.a. 963-1009 (exon 14) and N-terminal GST-tag, expressed in a Baculovirus infected Sf9 cell expression system. MW=71 kDa.
Format: Aqueous buffer solution
Formulation: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.25 mM DTT, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol.
Genbank: NM_000245
Storage Stability: At least 6 months at -80°C.
Supplied As: Aqueous buffer solution.
Tags: N-terminal GST-tag
Uniprot: P08581
Warnings: Avoid multiple freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Giordano, S. et al, Oncogene (11): 1383-8, 1989.
2. Iyer, A. et al, Cell Growth Differ. 1(2): 87-95, 1990.