C1q antibody (JL-1) (FITC)

Clone Name: JL-1

Application Note: *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Specificity/Sensitivity: The monoclonal antibody JL-1 is reactive with the collagen-like region (CLR) only, which is the same region to which autoantibodies in mice and humans are binding. Anti-C1q autoantibodies deposit in glomeruli together with C1q but induce overt renal disease only in the context of glomerular immune complex disease. This provides an explanation why anti-C1q antibodies are especially pathogenic in patients with SLE.

Form: Liquid

Buffer (with preservative): 0.2 μm filtered PBS, 1% BSA, 0.02% sodium azide.

Concentration: 0.1 mg/ml (Please refer to the vial label for the specific concentration.)

Uniprot ID: P02746/P02747/P02745

Antigen Species: Mouse

Immunogen: Purified mouse C1q

Purification: Protein G purified

Conjugation: FITC

Full Name: complement C1q A chain/complement C1q B chain/complement C1q C chain

• SKU: GTX54404-06-100
• Manufacturer: GeneTex
• Manufacturer SKU: GTX54404-06-100
• Green Labware: No
• Package Unit: 100 μg
• Quantity Unit: STK
• Reactivity: Human, Rat (Rattus)
• Clonality: Monoclonal
• Application: Immunofluorescence, Immunohistochemistry (frozen), Western Blotting, Functional Assay, Immunocytochemistry
• Isotype: IgG2b
• Human Gene ID: 712
• Host: Mouse