Clone Name: GT933
Product Description: Carbohydrate antigen 19-9 (CA 19-9), also known as sialyl-LewisA, is a tetrasaccharide with the sequence Neu5Acα2-3Galβ1-3[Fucα1-4]GlcNAcβ. It is used clinically to assist in the diagnosis of pancreatic cancer, but is more widely utilized to monitor therapy and detect recurrences in diagnosed cases. CA 19-9 is also elevated in many other diseases, including cholangiocarcinoma, colorectal cancer, hepatocellular carcinoma, and cirrhosis. GeneTex’s CA 19-9 mouse monoclonal antibody [GT933] demonstrates superior sensitivity for western blot, immunohistochemistry, and immunocytochemistry in comparative testing against other well-known CA 19-9 antibodies. Most significantly, glycan array interrogation using this antibody establishes that it is specific for sialyl-LewisA.
Application Note: WB: 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Specificity/Sensitivity: This antibody specifically detects sialyl-Lewis <sup>A</sup> (CA 19-9), but not sialyl-Lewis <sup>X</sup>.
Form: Liquid
Buffer (with preservative): PBS, no preservative.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Immunogen: The immunogen used to generate this antibody corresponds to CA19-9.
Purification: Affinity purified by Protein G.
Conjugation: Unconjugated
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