Abbreviation: CABP1
Target Synonym: CALBRAIN;HCALB_BR;CABP1
Conjugation: Unconjugated
UNIProt ID: Q9NZU7
Background: Calcium binding proteins are an important component of calcium mediated cellular signal transduction. This gene encodes a protein that belongs to a subfamily of calcium binding proteins which share similarity to calmodulin. The protein encoded by this gene regulates the gating of voltage-gated calcium ion channels. This protein inhibits calcium-dependent inactivation and supports calcium-dependent facilitation of ion channels containing voltage-dependent L-type calcium channel subunit alpha-1C. This protein also regulates calcium-dependent activity of inositol 1,4,5-triphosphate receptors, P/Q-type voltage-gated calcium channels, and transient receptor potential channel TRPC5. This gene is predominantly expressed in retina and brain. Alternative splicing results in multiple transcript variants encoding disinct isoforms. [provided by RefSeq, Jul 2012]
Concentration: 1mg/mL
Immunogen: A synthetic peptide of human CABP1
Dilution: WB 1:500-1:2000,IHC 1:50-1:200
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