Application Note: WB: 1:500-1:2000. IHC-P: 1:50-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 42
Specificity/Sensitivity: We do not recommend use of this product for Bovine,Dog,Horse,Pig,Rabbit,Sheep.
Form: Liquid
Buffer (with preservative): PBS pH 7.4, 150 mM NaCl, 50% glycerol, 0.02% sodium azide.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3. [provided by RefSeq, Aug 2017]
Uniprot ID: P41597
Antigen Species: Human
Immunogen: A synthesized peptide derived from human CCR2(Accession P41597), corresponding to amino acid residues N110-L134.
Purification: Purified by antigen-affinity chromatography
Conjugation: Unconjugated
Full Name: C-C motif chemokine receptor 2
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