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Clone Name: 1J13
Application Note: FACS: 1:100 - 1:800. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 42
Form: Liquid
Buffer (with preservative): PBS, no preservative.
Concentration: 500 μg/ml (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3. [provided by RefSeq, Aug 2017]
Uniprot ID: P41597
Antigen Species: Human
Immunogen: Human CCR2 transfected 293 cells
Purification: Protein G purified
Conjugation: Unconjugated
Full Name: C-C motif chemokine receptor 2