Clone Name: LPFS2/2034R
Application Note: IHC-P: 1-2 μg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 29
Form: Liquid
Buffer (with preservative): 10mM PBS, 0.05% BSA, 0.05% Sodium azide.
Concentration: 200 μg/ml (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]
Uniprot ID: P26842
Antigen Species: Human
Immunogen: Recombinant human full-length CD22 protein
Purification: Protein A/G purified
Conjugation: Unconjugated
Full Name: CD27 molecule