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Encompassing Amino Acids: 19-152
Applications: Useful for the study of protein-protein interaction and in vitro and in vivo protein function studies.
Description: Human secreted CD28-Fc fusion protein, also known as TP44, GenBank Accession No. NM_006139, a.a 19-152, expressed in a HEK293 cell expression system. MW = 41.4 kDa (monomer). This protein runs at a higher M.W. by SDS-PAGE due to glycosylation.
Format: Aqueous buffer solution
Formulation: 8 mM PBS pH 7.4, 110 mM NaCl, 2.2 mM KCl and 20% glycerol
Genbank: NM_006139
Storage Stability: At least 6 months at -80°C.
Tags: C-terminal Fc fusion (Human IgG1)
Uniprot: P10747
Warnings: Avoid freeze/thaw cycles. Protein may be diluted to ≥100 µg/ml in PBS + glycerol and stored at -80°C.
Biosafety Level: Not applicable (BSL-1)
References: 1. Byrum, J.N., Van Komen, J.S., Rodgers, W., J. Immunol. 2013 Sep 15;191(6):3073-3081.2. Legat, A., et al., Front Immunol. 2013 Dec 19;4:455.