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Encompassing Amino Acids: 43-300(end)
Application: Useful for studying protein binding and for screening small molecules and antibodies
Assay Conditions: Assay was done according to CD38 Inhibitor Screening Assay Kit (Cyclase Activity) (BPS Bioscience #71275) with CD38 titrated from 66.3 ng/µl (994 ng/rxn) to 1 ng/µl.
Description: Human CD38, also known as cluster of differentiation 38 and cyclic ADP ribose hydrolase with C-terminal His-tag, GenBank Accession No. NM_001775, a.a. 43-300 expressed in a HEK293 cell expression system. MW = 31 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation.
Format: Aqueous buffer solution
Formulation: 8 mM Na Phosphate pH 7.4, 110 mM NaCl, 2.2 mM KCl and 20% glycerol.
Genbank: NM_001775
Purity: ≥90%
Storage Stability: At least 6 months at -80°C. Avoid freeze/thaw cycles. Protein may be diluted to ≥ 100 µg/ml in PBS + glycerol and stored at -80°C.
Tags: C-terminal His-Tag
Uniprot: P28907
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1.Damle, R. et al., Blood. 1998; 94: 1840-1847.2.Howard, M. et al., Science. 1993; 262(5136): 1056-1059.
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