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Encompassing Amino Acids: 43-300(end)
Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Assay Conditions: Assay was done according to CD38 Inhibitor Screening Assay Kit (Cyclase Activity) (BPS Bioscience #71275) with CD38 titrated from 66.3 ng/µl (994 ng/rxn) to 1 ng/µl.
Description: Recombinant human CD38 (CD38 molecule) encompassing amino acids 43 to 300 (end). This construct contains a C-terminal His-tag (6xHis). The recombinant protein was affinity purified. HiP™ indicates a high purity protein (≥90% pure) and less than 10% aggregation as measured by gel filtration.
Format: Aqueous buffer solution.
Formulation: 8 mM phosphate pH 7.4, 110 mM NaCl, 2.2 mM KCl, 20% glycerol
Genbank: NM_001775
Host Cell Line: HEK293
Purity: ≥90%
Storage Stability: At least 6 months at -80°C.
Tags: C-terminal His-Tag
Uniprot: P28907
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1.Damle, R. et al., Blood. 1998; 94: 1840-1847.2.Howard, M. et al., Science. 1993; 262(5136): 1056-1059.