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Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Description: Human secreted CD44, also known as epican, extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, or phagocytic glycoprotein I (PGP-1), GenBank Accession No. NM_000610, a.a. 21-220 expressed in a HEK293 cell expression system, fused at the C-terminus to the Fc portion of human IgG1, and enzymatically biotin-labeled using Avi-tag™ technology. MW = 50.6 kDa (monomer). This protein runs at a higher M.W. by SDS-PAGE due to glycosylation.
Format: Aqueous buffer solution.
Formulation: 8 mM Na Phosphate pH 7.4, 110 mM NaCl, 2.2 mM KCl and 20% glycerol.
Genbank: NM_000610
Storage Stability: At least 6 months at -80°C.
Tags: Fc fusion (Human IgG1), Biotin-labeled
Uniprot: P16070
Warnings: Avoid freeze/thaw cycles. Protein may be diluted to ≥100 µg/ml in PBS + glycerol and stored at -80°C.
Biosafety Level: Not applicable (BSL-1)
References: 1. Aruffo, A., et al., Cell. 1990; 61(7): 1303-1313.
2. Screaton, G.R., et al., Proc. Natl. Acad. Sci. (USA). 1992; 89(24): 12160-12164.
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