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Applications: Useful for studies of protein function and protein-protein interaction.
Description: Human CD46-C, also known as membrane co-factor protein, GenBank Accession No. BC_030594, a.a. 35-285 and 301-328 with C-terminal His-tag, expressed in a HEK293 cell expression system. MW = 35.2 kDa (precursor), 32.8 kDa (mature). Note: this protein is expressed with a 34 amino acid signal sequence that is cleaved after secretion and is heavily glycosylated, resulting in a protein that runs at a higher apparent MW.
Format: Aqueous buffer solution
Formulation: 8 mM phosphate, pH 7.4,110 mM NaCl, 2.2 mM KCl, and 20%glycerol.
Genbank: BC_030594
Host Cell Line: HEK293
Storage Stability: At least 6 months at -80°C
Tags: C-terminal His-tag
Uniprot: P15529
Warnings: Avoidfreeze/thaw cycles. Storing diluted protein isnot recommended, if necessary, use carrierprotein (BSA 0.1 - 0.5%).
Biosafety Level: Not applicable (BSL-1)
References: 1. Liszewski, MK., Atkinson, JP., J. Immunol. 1996; 156(11):4415-4421.
2. Gerlier, D., et al., Gen. Virol. 1994. 75(Pt 9):2162-2171.