CD49c

CD49c, Monoclonal, IgG1, Host: Mouse, FITC

Clone: VJ1/6.

Conjugate: FITC.

Immunogen: Integrin alpha 3.

Storage Buffer: The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3).

It is a type I transmembrane glycoprotein which is proteolytically cleaved into two disulfide linked fragments of 125 kD and 30 kD. CD49c forms a heterodimer with integrin β1 (α3β1, CD49c/CD29, VLA-3) and is expressed by many types of adhesion cells, such as endothelial cells, epithelial cells, and dermal fibroblasts. Weak expression has been reported on leukocytes. VLA-3 plays a role in cell-cell and cell-matrix adhesion through binding Kalinin, collagen, laminin-1, laminin-5, entactin, and fibronectin.

• SKU: IMS49CF-100T
• Manufacturer: Immunostep
• Manufacturer SKU: 49CF-100T
• Package Unit: 100 Tests
• Quantity Unit: PAK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Flow Cytometry
• Isotype: IgG1
• Human Gene ID: 3675
• Host: Mouse
• Conjugate: Conjugated, FITC