Clone: ALC1/1.
Conjugate: PE.
Immunogen: Tissue / cell preparation (JM leukemia line).
Storage Buffer: The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3).
Recommended Usage: CD49b, clone ALC1/1 is a mAb primarily expressed on T and B lymphocytes and weakly expressed on monocytes. This reagent is effective for direct IF staining of human tissue for FCM analysis using ≤1 μg/106 cells.
CD49d (Anti–VLA-α-4) recognizes the 150-kilodalton (kd) α-chain of very-late antigen (VLA)-4, a member of the integrin family of cell adhesion molecules. VLA-4, like other integrins, is a noncovalently associated heterodimeric glycoprotein composed of α and ß subunits and is involved in cell–cell and cell–extracellular matrix interactions. The ß-chain of the VLA-4 complex is the CD29 antigen, a 130-kd glycoprotein.
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