Clone Name: C86/2160R
Application Note: WB: 1-2 μg/ml. ICC/IF: 1-2 μg/ml. IHC-P: 1-2 μg/ml. FACS: 1-2 μg/million cells. ELISA: 2-4 μg/ml (for coating). *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 38
Form: Liquid
Buffer (with preservative): 10mM PBS, 0.05% BSA, 0.05% Sodium azide.
Concentration: 200 μg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]
Uniprot ID: P42081
Antigen Species: Human
Immunogen: Recombinant human full-length CD86 protein
Purification: Protein A/G purified
Conjugation: Unconjugated
Full Name: CD86 molecule
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