Application Note: WB: 1:1000-1:3000. ICC/IF: 1:200. IP: 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 63
Form: Liquid
Buffer (with preservative): Filter-sterilized PBS, 50% Glycerol, no preservative.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. [provided by RefSeq, Jul 2008]
Uniprot ID: Q99741
Antigen Species: Human
Immunogen: Recombinant GST-human CDC6 (1-326 amino acids) expressed in E. coli
Purification: Purified by antigen-affinity chromatography
Conjugation: Unconjugated
Full Name: cell division cycle 6
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