CDK2AP1 Polyclonal Antibody, Rabbit

Abbreviation: CDK2AP1

Target Synonym: CDK2AP1; DOC1; DORC1; ST19; doc-1; p12DOC-1; cyclin-dependent kinase 2-associated protein 1

Conjugation: Unconjugated

UNIProt ID: O14519

Background: The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human CDK2AP1

Dilution: WB 1:500-1:2000

• SKU: ELSE-AB-92415-60
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-E-AB-92415-60
• Green Labware: No
• Package Unit: 60 µl
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Polyclonal
• Application: Western Blotting
• Isotype: IgG
• Host: Rabbit