cis-4-Hydroxy-L-proline (hydrochloride), CAS 441067-49-8

Product Description: cis-4-Hydroxy-L-proline hydrochloride is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). cis-4-Hydroxy-L-proline hydrochloride is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Applications: Cancer-programmed cell death

Formula: C5H10ClNO3

References: [1]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985./[2]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337.

CAS Number: 441067-49-8

Molecular Weight: 167.59

Compound Purity: 97.0

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Linker;PROTAC Linkers

• SKU: MEXHY-W019213-5G
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W019213-5G
• Package Unit: 5 g
• Quantity Unit: STK